Read e-book online Advances in Immunology, Vol. 16 PDF

By F.J. Dixon, Henry G. Kunkel (Eds.)

ISBN-10: 012022416X

ISBN-13: 9780120224166

Show description

Read or Download Advances in Immunology, Vol. 16 PDF

Best biology books

Microchip-Based Assay Systems: Methods and Applications by Pierre N. Floriano PDF

This quantity explores contemporary development within the microelectronics area, the consequent miniaturization of part gadget beneficial properties to nanometer dimension debris, and the consequent development within the improvement and use of microchip-based recommendations in top laboratories all over the world. whereas the world of microelectronics is confronted with daunting demanding situations, it offers interesting new advances that can translate into items akin to sensors and units that use nanometer-sized development blocks for real-world functions.

New PDF release: Genomics Protocols

Because the first version, released in 2001, genomics study has taken nice strides. In Genomics Protocols, 2d version, a staff of specialist researchers percentage the most up-tp-date details in a box that has lately switched emphasis from gene id to sensible genomics and the characterization of genes and gene items.

Download e-book for iPad: The Liver: Biology and Pathobiology, Fifth Edition by -Author-

Content material: bankruptcy 1 Organizational rules of the Liver (pages 1–15): Joe W. GrishamChapter 2 Embryonic improvement of the Liver (pages 17–25): Roque Bort and Kenneth S. ZaretChapter three Microtubules, Actin Filaments and Motor? Mediated Vesicular shipping (pages 27–43): Ronald R. Marchelletta and Sarah F.

Extra resources for Advances in Immunology, Vol. 16

Example text

Thus, by comparing the activities of Fab, pFc’, Fc, and Facb, it is possible to localize various biological activities and antigenic specificities to each of the threc homology regions. :NT OF V. \ l tl OUS ANTICKNSTO I>IFFEItENT FIL~CMENTS OF IMMUNOGLOBULIN G Antigeri* Inimriiioglobriliri fragrneiits y2-3 71-23 I g ( 2 iirisplit F(ab')? 12 The 72-3 is located i n Fc oritaide pFc' and thus resides in CH2; yl-2-3 is in the ~ F c ' region and thus in CH3; tmd y 2k Fab is in the constant portion of Fd and thus in CHI.

1970a,b) (Fig. 3). Therc arc also subfragments of pFc’. By further digestion with trypsin about 7 N-tcrminal residues are lost, but the tryptic fragment still extends to the C-terminal cncl. This fragment has a slightly faster electrophoretic mobility than pFc’, although it contains all the same genetic antigens as found in pFc’. Finally, by papain digestion, an Fc’ fragment that lacks 8-9 N-terminal residues but also 13 or 14 Cterminal residues as compared to pFc’ (Figs. 4 and 5 ) can be obtained.

Immunoelectroplloresis of pFc' fragnients from each of the four I& subclasses. 2, and IgC3 pFc' fragments, but IgG4 pFc' has a faster mobility. ) Papain I Fc fragment Lys Ile ) pFc' fragment (334 336 Trypsin 4 tFc' fragment + fh y motr y psin ( I336 le A 339) h Papain ( kg) ctFc' fragment Papain Fc' fragment - N-terminus C-terminus - Frc. 5. Schelnatic illustration o f different subfragments of Fc and their probable molecular localization. The numbering corresponds to that of the Eu protein. Residue 446 is the C-tenninal residue.

Download PDF sample

Advances in Immunology, Vol. 16 by F.J. Dixon, Henry G. Kunkel (Eds.)


by Anthony
4.2

Rated 4.61 of 5 – based on 37 votes